Primary Identifier | MGI:3029359 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Prkaa1 |
Transmission | Germline | Strain of Origin | 129S2/SvPas |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Sequence encoding amino acids 97 through 157, which make up a portion of the catalytic domain, was replaced with an IRES-betageo cassette inserted by homologous recombination. Protein was undetected by Western blot analysis of liver and skeletal muscle extracts prepared from homozygous mutant mice. |