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Allele : Prkaa1<tm1Sbj> protein kinase, AMP-activated, alpha 1 catalytic subunit; targeted mutation 1, Sebastian B Jorgensen

Primary Identifier  MGI:3029359 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Prkaa1
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  Sequence encoding amino acids 97 through 157, which make up a portion of the catalytic domain, was replaced with an IRES-betageo cassette inserted by homologous recombination. Protein was undetected by Western blot analysis of liver and skeletal muscle extracts prepared from homozygous mutant mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Prkaa1<tm1Vio>,
  • alpha1AMPK<->,
  • AMPKalpha1<->,
  • Ampk<->,
  • alpha1AMPK<->,
  • Ampk<->,
  • Prkaa1<tm1Vio>,
  • AMPKalpha1<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

118 Publication categories