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Allele : Cd1d1<tm1.1Aben> CD1d1 antigen; targeted mutation 1.1, Albert Bendelac

Primary Identifier  MGI:5056283 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Cd1d1
Transmission  Germline Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
description  Because the C57BL/6 ES cells used to generate the allele contain a natural frameshift mutation in Cd1d2 that prevents its surface expression, deletion of Cd1d1 is sufficient to abolish all CD1D protein from the cell surface.
molecularNote  Exons 2-6 were flanked by loxP sites. Flp-mediated recombination removed the neo cassette.
  • mutations:
  • Insertion
  • synonyms:
  • CD1.1 Conditional,
  • cd1d1<fl>,
  • Cd1d1/Cd1d2<tm1.1Aben>,
  • CD1d<fl>,
  • CD1d<fl>,
  • cd1d1<fl>,
  • Cd1d1/Cd1d2<tm1.1Aben>,
  • CD1.1 Conditional
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

5 Carried By

Trail: Allele

0 Driven By

14 Publication categories

Trail: Allele