Primary Identifier | MGI:3487301 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Hipk2 |
Transmission | Germline | Strain of Origin | 129X1/SvJ |
Is Recombinase | false | Is Wild Type | false |
molecularNote | LacZ and PGK-neo replaced exon 3 (the first coding exon) and were inserted in frame with the first ATG via homologous recombination. Northern analysis and RT-PCR confirmed the absence of mRNA in MEFs and trigeminal ganglia, respectively. Beta-galactosidase was expressed in developing trigeminal ganglion and dorsal root ganglion. |