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Allele : Hipk2<tm1Ejh> homeodomain interacting protein kinase 2; targeted mutation 1, Eric J Huang

Primary Identifier  MGI:3487301 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Hipk2
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  LacZ and PGK-neo replaced exon 3 (the first coding exon) and were inserted in frame with the first ATG via homologous recombination. Northern analysis and RT-PCR confirmed the absence of mRNA in MEFs and trigeminal ganglia, respectively. Beta-galactosidase was expressed in developing trigeminal ganglion and dorsal root ganglion.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

15 Publication categories