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Publication : The lpr and gld genes in systemic autoimmunity: life and death in the Fas lane.

First Author  Cohen PL Year  1992
Journal  Immunol Today Volume  13
Issue  11 Pages  427-8
PubMed ID  1282318 Mgi Jnum  J:3363
Mgi Id  MGI:51876 Doi  10.1016/0167-5699(92)90066-G
Citation  Cohen PL, et al. (1992) The lpr and gld genes in systemic autoimmunity: life and death in the Fas lane [published erratum appears in Immunol Today 1993 Feb;14(2):97]. Immunol Today 13(11):427-8
abstractText  The single gene lpr and gld models of spontaneous systemic autoimmunity have attracted much attention in recent years. Here, Philip Cohen and Robert Eisenberg describe the fascinating recent findings that the lpr and gld [corrected] phenotypes result from defects in the Fas gene and, perhaps, in the ligand for fas, respectively.
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