First Author | Cohen PL | Year | 1992 |
Journal | Immunol Today | Volume | 13 |
Issue | 11 | Pages | 427-8 |
PubMed ID | 1282318 | Mgi Jnum | J:3363 |
Mgi Id | MGI:51876 | Doi | 10.1016/0167-5699(92)90066-G |
Citation | Cohen PL, et al. (1992) The lpr and gld genes in systemic autoimmunity: life and death in the Fas lane [published erratum appears in Immunol Today 1993 Feb;14(2):97]. Immunol Today 13(11):427-8 |
abstractText | The single gene lpr and gld models of spontaneous systemic autoimmunity have attracted much attention in recent years. Here, Philip Cohen and Robert Eisenberg describe the fascinating recent findings that the lpr and gld [corrected] phenotypes result from defects in the Fas gene and, perhaps, in the ligand for fas, respectively. |