| Primary Identifier | MGI:3641234 | Allele Type | Chemically induced (ENU) |
| Gene | Myd88 | Inheritance Mode | Recessive |
| Strain of Origin | C57BL/6 | Is Recombinase | false |
| Is Wild Type | false |
| description | Genbank ID for this allele: DQ790886 |
| molecularNote | This mutation, identified in a screen of G3 progeny of ENU treated mice for responses to various toll-like receptor ligands, is an A-to-G transition resulting in replacement of tyrosine with cysteine at amino acid 116 (Y116C), between the death domain (aa 19-109) and the toll-interleukin 1 receptor (TIR) domain (aa 160-296) of the protein. |
