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Allele : Rab3gap1<em1(IMPC)J> RAB3 GTPase activating protein subunit 1; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:6294152 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Rab3gap1
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GACTTATCACAGTGGCTATT and TAGTACTGCATCTGAAGAAG, which resulted in a 500 bp deletion beginning at Chromosome 1 position 127,888,975 bp and ending after 127,889,474 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001274408 (exon 4) and 367 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 50 and early truncation 12 amino acids later.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele