| Primary Identifier | MGI:5648202 | Allele Type | Chemically induced (ENU) |
| Gene | b2b3260Clo | Strain of Origin | C57BL/6J |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | B2B/CvDC |
| description | Summative Diagnosis: Mutant Type 1: Cardiovascular phenotypes: Dysplastic semilunar valves, persistent truncus arteriosus (PTA), transposition of the great arteries (TGA) Noncardiovascular phenotype: short snout, exencephaly, preaxial digit duplication, renal anomalies Mutant Type 2: Cardiovascular phenotypes: transposition of the great arteries, atrioventricular septal defect with cushion valves, myocardial noncompaction Noncardiovascular phenotype: cleft palate, hypoplastic malformed thymus, kidney cysts |
| molecularNote | This ENU-induced mutation was isolated in a screen at the University of Pittsburgh. More than one mutation in this line results in a discernible phenotype in a homozygous recessive screen. At least two segregating phenotype groups are identified. See Tbc1d32b2b3260.1Clo and b2b3260.2Clo. |
