Primary Identifier | MGI:3843052 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Ep300 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Acetyltransferase (AT) activity was ablated via the incorporation of engineered point mutations at the endogenous locus. The mutations substitute alanine and serine for tryptophan and tyrosine (WY(1466-1477)AS). This allele was used to generate Ep300tm1Reck. |