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Allele : Rev1<em2Gpc> REV1, DNA directed polymerase; endonuclease-mediated mutation 2, Gerry P Crossan

Primary Identifier  MGI:7643779 Allele Type  Endonuclease-mediated
Gene  Rev1 Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
molecularNote  Aspartic acid codon 568 (GAT) and glutamic acid codon 569 (GAA) in exon 11 were changed to alanine (GCG, GCA) (p.DE568_569delinsAA) using an sgRNA and an ssODN template with CRISPR/Cas9 technology. The mutations render the encoded peptide catalytically inactive.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Rev1<AA>,
  • Rev1<AA>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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2 Publication categories

Trail: Allele