Primary Identifier | MGI:7643779 | Allele Type | Endonuclease-mediated |
Gene | Rev1 | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Aspartic acid codon 568 (GAT) and glutamic acid codon 569 (GAA) in exon 11 were changed to alanine (GCG, GCA) (p.DE568_569delinsAA) using an sgRNA and an ssODN template with CRISPR/Cas9 technology. The mutations render the encoded peptide catalytically inactive. |