Primary Identifier | MGI:4459449 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Shoc2 |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | LoxP sites were inserted to flank exon 3 of the Shoc2 (Sur-8) gene. The targeting vector also contained an frt-flanked neomycin resistance cassette. The vector was electroporated into W4 ES cells. Mutant mice were crossed to Actin-FLPe transgenic mice to remove the neo cassette, leaving the floxed allele. |