Primary Identifier | MGI:5696736 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(Camk2a-SNCA*)2Mgsp |
Strain of Origin | (C57BL/6J x CBA/J)F1/J | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A human 120-amino acid truncated alpha-synuclein cDNA is under the control of the Camk2 1.3 alpha promoter. Three lines were generated (1, 2, and 3). These mice were crossed to C57BL/6JOlaHsd mice which lack alpha-synuclein as a result of a spontaneous deletion of the alpha-SNCA locus. |