Primary Identifier | MGI:2447590 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(SV40-BCL2L1)169Nnz |
Strain of Origin | (C57BL/6 x SJL/J)F2 | Is Recombinase | false |
Is Wild Type | false |
description | Seven transgenic founders were created and transgenic lines were established. Lines bcl-x-169 and bcl-x-86 were used for analysis. |
molecularNote | The transgene consists of an SV40 promoter, Igh enhancer, and a human BCL2L1 cDNA. The Igh enhancer was used to target transgene expression to T lymphocytes. Western blot analysis verified transgene expression in the thymus. |