| Primary Identifier | MGI:5476799 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(Prnp-PRNP)110Jmto |
| Strain of Origin | (C57BL/6 x CBA)F1 x 129P2/OlaHsd-Prnp<tm2Edin> | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The open reading frame of the bovine prion protein gene was inserted into an expression vector containing the mouse prion protein promoter, exon 1, intron 1, exon 2 and 3' untranslated region. Bovine prion protein expression in brains of homozygous transgenic mice of this line, as determined by western blot analysis, is 8-fold that observed in cow brain homogenate; none is detected in spleen, heart, skeletal muscle, testis or kidney of transgenic mice. |
