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Allele : Pde4c<tm1.1(KOMP)Wtsi> phosphodiesterase 4C, cAMP specific; targeted mutation 1.1, Wellcome Trust Sanger Institute

Primary Identifier  MGI:5585589 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Pde4c
Transmission  Germline Strain of Origin  C57BL/6N-A<tm1Brd>
Is Recombinase  false Is Wild Type  false
Project Collection  KOMP-CSD
molecularNote  The insertion of the L1L2_Bact_P cassette created a deletion of size 4555 starting at position 71197807 and ending at position 71202362 of Chromosome 8 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site was followed by neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site, and subsequent Cre-mediated excision deleted the neomycin selection cassette.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

Trail: Allele

0 Driven By

11 Publication categories

Trail: Allele