| Primary Identifier | MGI:7565496 | Allele Type | Targeted |
| Attribute String | Conditional ready | Gene | Fbxl12 |
| Transmission | Germline | Strain of Origin | C57BL/6 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The targeting vector obtained from KOMP is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of the targeted exon 4. The critical exon 4 is thus flanked by loxP sites. The neomycin resistance gene was removed via flp-mediated recombination resulting in a âconditional readyâ (floxed) allele. |
