First Author | Hunsicker PR | Year | 1969 |
Journal | Mouse News Lett | Volume | 40 |
Pages | 41 | Mgi Jnum | J:13492 |
Mgi Id | MGI:61679 | Citation | Hunsicker PR (1969) White-based brown, BW. Mouse News Lett 40:41 |
abstractText | Full text of MNL contribution: 2. White-based brown, Bw. This mutation, which was found following 600r low-dose-rate gamma irradiation to spermatogonia, resembles BLt in some respects but differs from it in others. As in the case of BLt, there is pigment reduction at the base of the hair and this is more extreme in homozygotes than in heterozygotes. However, whereas BLt/B is, according to description (GM 2, p. 49), Ãphenotypically indistinguishableà from Blt/b, there is a marked difference between Bw/B and Bw/b. In Bw/B, only the extreme base of the hair is light, the remainder being only barely distinguishable from B/B dorsally, though clearly lighter (dark grey?) ventrally; the eyes appear full colored. In Bw/b, on the other hand, about one-quarter to one-third of the hair, proximally, is near-white; the pigmented portions resemble b/b (rather than B/B); and eye-pigment, also, grossly resembles that of b/b both at birth and in adults. Bw/Bw is similar to Bw/b, in all respects except that the proximal, near-white portion of the hair is about twice as wide. Although the symbol Bw is provisionally used here, close linkage of an independent mutation has not yet been ruled out. Tests are in progress. (Hunsicker). |