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Publication : Strong cytolytic activity of natural killer cells is neither necessary nor sufficient for preimmune resistance to Toxoplasma gondii infection.

First Author  Johnson LL Year  1995
Journal  Nat Immun Volume  14
Issue  4 Pages  209-15
PubMed ID  8696010 Mgi Jnum  J:113057
Mgi Id  MGI:3664390 Citation  Johnson LL, et al. (1995) Strong cytolytic activity of natural killer cells is neither necessary nor sufficient for preimmune resistance to Toxoplasma gondii infection. Nat Immunol 14(4):209-15
abstractText  That strong cytolytic activity of natural killer (NK) cells is neither necessary nor sufficient for defense against acute Toxoplasma gondii infection is demonstrated. T. gondii-infected anti-interferon (IFN)-gamma-treated mice and IFN-gamma gene knockout mice died despite good induction of NK activity, while infected beige mice, deficient in NK cytolytic activity, survived.
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