| First Author | Jones-Carson J | Year | 1995 |
| Journal | J Infect Dis | Volume | 171 |
| Issue | 6 | Pages | 1664-7 |
| PubMed ID | 7769315 | Mgi Jnum | J:25930 |
| Mgi Id | MGI:73633 | Doi | 10.1093/infdis/171.6.1664 |
| Citation | Jones-Carson J, et al. (1995) Defective killing of Candida albicans hyphae by neutrophils from beige mice. J Infect Dis 171(6):1664-7 |
| abstractText | The candidacidal activity of neutrophils from BALB/c, C.B-17 +/+, C.B-17 scid/scid, scid/scid-bg/bg, C57BL/6 bg/+, C57BL/6 bg/bg, NIH III bg/bg-nu/+, and bg/bg-nu/nu mice was assessed. Killing of blastoconidia was moderately deficient with neutrophils from 2 strains of homozygous beige mice; however, neutrophils from all homozygous beige strains had a significantly decreased capacity to kill Candida albicans hyphae. This is the first demonstration of a decreased capacity of beige mouse neutrophils to kill C. albicans hyphae. The latter defect could be related to the enhanced susceptibility of beige mice to candidiasis. |
