First Author | Ahmed F | Year | 1985 |
Journal | J Hered | Volume | 76 |
Issue | 4 | Pages | 311-2 |
PubMed ID | 4031470 | Mgi Jnum | J:7980 |
Mgi Id | MGI:56449 | Doi | 10.1093/oxfordjournals.jhered.a110101 |
Citation | Ahmed F, et al. (1985) Lysosomal mutations inhibit lipofuscinosis of the spleen in C57BL mice. J Hered 76(4):311-2 |
abstractText | Beige, bg, and reduced pigmentation, rp, are recessive mutations affecting lysosomal function. Homozygosity for beige prevented lipofuscinosis of the spleen in C57BL mice and its incidence was greatly reduced by homozygosity for rp. Dilute (d) homozygotes, with normal lysosomes, were susceptible to lipofuscinosis even though their melanosomes were more severely affected than those of beige mice. |