| First Author | Shultz LD | Year | 2007 |
| Journal | Nat Rev Immunol | Volume | 7 |
| Issue | 2 | Pages | 118-30 |
| PubMed ID | 17259968 | Mgi Jnum | J:142414 |
| Mgi Id | MGI:3821495 | Doi | 10.1038/nri2017 |
| Citation | Shultz LD, et al. (2007) Humanized mice in translational biomedical research. Nat Rev Immunol 7(2):118-30 |
| abstractText | The culmination of decades of research on humanized mice is leading to advances in our understanding of human haematopoiesis, innate and adaptive immunity, autoimmunity, infectious diseases, cancer biology and regenerative medicine. In this Review, we discuss the development of these new generations of humanized mice, how they will facilitate translational research in several biomedical disciplines and approaches to overcome the remaining limitations of these models. |
