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Publication : Lysosomal mutations increase susceptibility to anaesthetics.

First Author  Ahmed F Year  1989
Journal  Experientia Volume  45
Issue  11-12 Pages  1133-5
PubMed ID  2513223 Mgi Jnum  J:29294
Mgi Id  MGI:77039 Doi  10.1007/BF01950180
Citation  Ahmed F, et al. (1989) Lysosomal mutations increase susceptibility to anaesthetics. Experientia 45(11-12):1133-5
abstractText  The anaesthetic responses of homozygous mutant mice were compared with those of their normal heterozygous littermates. The two recessive mutations studied were beige (bg) and reduced pigmentation (rp). Homozygosity for either significantly increased the sleeping time of both sexes after treatment with pentobarbital, tribromoethanol or the steroid anaesthetic alphaxalone.
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