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Publication : Prolonged longevity of hypopituitary dwarf mice.

First Author  Bartke A Year  2001
Journal  Exp Gerontol Volume  36
Issue  1 Pages  21-8
PubMed ID  11162909 Mgi Jnum  J:66980
Mgi Id  MGI:1929568 Doi  10.1016/s0531-5565(00)00205-9
Citation  Bartke A, et al. (2001) Prolonged longevity of hypopituitary dwarf mice. Exp Gerontol 36(1):21-8
abstractText  In two types of mutant dwarf mice, congenital deficiencies in pituitary function are associated with remarkably increased life expectancy. In this review, we will describe the key phenotypic characteristics of these animals, the evidence that they exhibit delayed aging, and the mechanisms that are suspected to account for their prolonged longevity.
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