| First Author | Nissley SP | Year | 1980 |
| Journal | Horm Metab Res | Volume | 12 |
| Issue | 4 | Pages | 158-64 |
| PubMed ID | 7390396 | Mgi Jnum | J:6340 |
| Mgi Id | MGI:54816 | Doi | 10.1055/s-2007-996230 |
| Citation | Nissley SP, et al. (1980) Somatomedin activity in sera of genetically small mice. Horm Metab Res 12(4):158-64 |
| abstractText | Somatomedin activity as determined by the stimulation of [3H]thymidine incorporation into chick embryo fibroblast DNA, was measured in extracts of sera from genetically small mice. Somatomedin activity was low in the sera from growth hormone deficient mice [Snell (dw/dw), Ames (df/df), and little (lit/lit)] whereas somatomedin activity was normal in serum from the pygmy (pg/pg)) mouse, a mutant proposed as a model for growth hormone resistance. GH treatment of the Snell mouse resulted in an increase in somatomedin activity to normal levels. |
