First Author | Heiniger HJ | Year | 1976 |
Journal | J Natl Cancer Inst | Volume | 56 |
Issue | 5 | Pages | 1073-4 |
PubMed ID | 186616 | Mgi Jnum | J:5726 |
Mgi Id | MGI:54203 | Doi | 10.1093/jnci/56.5.1073 |
Citation | Heiniger HJ, et al. (1976) Effect of allelic substitutions at the hairless locus on endogenous ecotropic murine leukemia virus titers and leukemogenesis. J Natl Cancer Inst 56(5):1073-4 |
abstractText | Leukemia-prone hairless (HRS/J; hr/hr) mice had significantly higher leukemia virus titers than did the leukemia-resistant nonmutants (hr/ + and +/+). This difference was ascribed to the allelic substitution at a single gene locus; at 6 months of age it averaged 13-fold, immediately preceding the large divergence in leukemia incidence between the mutant and nonmutant mice. |