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Publication : The mahogany mouse mutation: further links between pigmentation, obesity and the immune system.

First Author  Jackson IJ Year  1999
Journal  Trends Genet Volume  15
Issue  11 Pages  429-31
PubMed ID  10529800 Mgi Jnum  J:58128
Mgi Id  MGI:1346757 Doi  10.1016/s0168-9525(99)01824-7
Citation  Jackson IJ (1999) The mahogany mouse mutation: further links between pigmentation, obesity and the immune system. Trends Genet 15(11):429-31
abstractText  Completely different lines of experimentation have identified attractin, a protein that seems to have multiple roles in regulating physiological processes. It affects the balance between agonist and antagonist at receptors on melanocytes, modifies behaviour and basal metabolic rate, and mediates an interaction between activated T cells and macrophages. It may well be a target for development of drugs to treat obesity.
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