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Publication : Hereditary demyelinating neuropathy in the trembler mouse.

First Author  Low PA Year  1975
Journal  J Neurol Sci Volume  26
Issue  4 Pages  565-74
PubMed ID  173808 Mgi Jnum  J:5612
Mgi Id  MGI:54089 Doi  10.1016/0022-510x(75)90057-x
Citation  Low PA, et al. (1975) Hereditary demyelinating neuropathy in the trembler mouse. J Neurol Sci 26(4):565-74
abstractText  The Trembler mouse suffers from a hereditary demyelinating neuropathy. Nerve conduction studies were performed on the sciatic nerve, median nerve and dorsal nerve of the tail. There was a prolonged terminal latency, and motor conduction velocities were less than 10 m/sec in all the nerves examined. The electrophysiological abnormalities correlate with the pathological findings of hypomyelination.
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