|  Help  |  About  |  Contact Us

Allele : Galc<twi> galactosylceramidase; twitcher

Primary Identifier  MGI:1856218 Allele Type  Spontaneous
Attribute String  Null/knockout Gene  Galc
Inheritance Mode  Recessive Strain of Origin  CE/J
Is Recombinase  false Is Wild Type  false
molecularNote  Sequence analysis comparisons of cDNA from livers of mice homozygous for this allele and +/+ mice showed a G to A transition at codon 355, changing it from tryptophan to a stop codon (p.W355*). Northern analysis showed absence of the most abundant mRNA of mouse galactocerebrosidase in mice homozygous for this allele.
  • mutations:
  • Single point mutation
  • synonyms:
  • twi,
  • galc-,
  • galc-,
  • twi
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

5 Carried By

Trail: Allele

0 Driven By

102 Publication categories

Trail: Allele