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Publication : Morphological features of degenerating oligodendrocytes in twitcher mice.

First Author  LeVine SM Year  1992
Journal  Brain Res Volume  587
Issue  2 Pages  348-52
PubMed ID  1525668 Mgi Jnum  J:2125
Mgi Id  MGI:50649 Doi  10.1016/0006-8993(92)91018-a
Citation  LeVine SM, et al. (1992) Morphological features of degenerating oligodendrocytes in twitcher mice. Brain Res 587(2):348-52
abstractText  The morphological features of degenerating oligodendrocytes in twitcher mice were examined by a modified iron histochemical technique. Oligodendrocytes in twitcher mice were found to have several features distinct from oligodendrocytes in normal mice; swellings at different sites along their processes, swollen soma and an increase in iron-rich, oval structures in their cytoplasm. In addition to changes in oligodendrocyte morphology, endothelial cells in brains of twitcher mice were found to be highly enriched with iron.
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