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Publication : Aberrant visual pathways in microphthalmic mice.

First Author  Hilbig H Year  1994
Journal  J Hirnforsch Volume  35
Issue  3 Pages  397-404
PubMed ID  7983371 Mgi Jnum  J:22569
Mgi Id  MGI:70428 Citation  Hilbig H, et al. (1994) Aberrant visual pathways in microphthalmic mice. J Hirnforsch 35(3):397-404
abstractText  We report results obtained in the microphthalmic strain of mice 944. Heterozygotes appear normal, but they produce litters in which typically between 2 and 5 offspring exhibit microphthalmia. As a result these animals are blind. Our investigations using the fluorescent tracer DiI show that in microphthalmic mice there is a small compensation for the missing retinal input by terminals or axon collaterals originating in the somatosensory thalamus. These morphological findings agree with somatosensory responses recorded in the visual cortex (EEG recordings).
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