| First Author | Funda D | Year | 1994 |
| Journal | Folia Biol (Praha) | Volume | 40 |
| Issue | 3 | Pages | 135-40 |
| PubMed ID | 7805935 | Mgi Jnum | J:20342 |
| Mgi Id | MGI:68439 | Citation | Funda D, et al. (1994) Hairlessness does not influence growth retardation in nude mice. Computer image analysis study. Folia Biol (Praha) 40(3):135-40 |
| abstractText | Ossification in 4-week-old nu/nu and nu/+ BALB/c and BFU mice was studied by X-ray analysis and by measurement of the thickness of the proximal tibial growth cartilage using CUE 4 Olympus computer image analysis. Not only altered architecture but also a significantly thinner proximal tibial growth plate was observed in athymic nu/nu as opposed to nu/+ and BFU mice. On the other hand, no significant differences were found between nu/+ and BFU littermates. Higher X-ray density of tail vertebrae was observed in nu/+ and BFU than in nu/nu mice. This comparison between athymic nu/nu and hairless euthymic BFU mice indicates that altered postnatal ossification in nude mice is not caused by hairlessness, but is due to other (immunological or endocrinological) differences. |
