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Publication : or-2J; a new remutation at ocular retardation (or) associated with sterility

First Author  Prochazka M Year  1990
Journal  Mouse Genome Volume  87
Pages  93 Mgi Jnum  J:30714
Mgi Id  MGI:78457 Citation  Prochazka M, et al. (1990) or-2J; a new remutation at ocular retardation (or) associated with sterility. Mouse Genome 87:93
abstractText  Full text of Mouse Genome contribution: Linkage of ocular retardation (or). Ocular retardation has been mapped using inversion In(12)25Rk which ÒinhibitsÓ recombination through loss of recombinant products over a major portion of chromosome 12. Males: In25 +/+ or; Females: + or/+ or; Parental phenotypic classes: In25 +/23; + or/24; Recombinant classes: none. The presence of the inversion in the backcross was ascertained as a dominant by the high frequency of first meiotic anaphase bridges observed in sectioned testes. Ocular retardation, apparently full penetrant, is recognized in homozygotes by bilateral closed eyelids at weaning. Crosses in progress with other markers on Chr 12 are confirming this assignment. (N.L. Hawes and Roderick).
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