| First Author | Dupouey P | Year | 1979 |
| Journal | Neurosci Lett | Volume | 12 |
| Issue | 1 | Pages | 113-8 |
| PubMed ID | 88695 | Mgi Jnum | J:6180 |
| Mgi Id | MGI:54657 | Doi | 10.1016/0304-3940(79)91490-3 |
| Citation | Dupouey P, et al. (1979) Immunochemical studies of myelin basic protein in shiverer mouse devoid of major dense line of myelin. Neurosci Lett 12(1):113-8 |
| abstractText | The myelin-deficient mutant Shiverer (Shi/Shi) lacks basic protein (MBP) in the myelin of its central nervous system (CNS). Less than 3% of the normal content in MBP is present in a brain extract of Shi/Shi as determined by radioimmunoassay. Indirect immunofluorescence is negative when using specific anti-MBP serum. The importance of Shi/Shi (as compared to other hypomelinating mutants) stems from the specificity of this genetic lesion, i.e. the lack of basic protein. |
