| Primary Identifier | MGI:1856163 | Allele Type | Radiation induced |
| Gene | Kitl | Inheritance Mode | Semidominant |
| Strain of Origin | (C3H/HeH x 101/H)F1 | Is Recombinase | false |
| Is Wild Type | false |
| description | The contrasted mutation was found in a neutron irradiation experiment. Heterozygotes are recognizable soon after birth by dark pigmentation of the genital papilla. The adult coat is slightly lighter than normal. Homozygotes also have dark external genitalia but a markedly diluted coat; they have a mild macrocytic anemia. Males are fertile but females are usually sterile (J:20215). |
| molecularNote | Pulse field gel electrophoresis using cDNA and genomic clones showed that this allele is an undefined rearrangement between 90 and 2.2Mb 5' to Kitl. Northern analysis showed that the mRNA transcript is of normal size but this allele exerts tissue-specific effects on transcript abundance. |
