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Publication : Panda, a new steel allele

First Author  Beechey CV Year  1986
Journal  Mouse News Lett Volume  74
Pages  92 Mgi Jnum  J:14075
Mgi Id  MGI:62252 Citation  Beechey CV, et al. (1986) Panda, a new steel allele. Mouse News Lett 74:92
abstractText  Full text of MNL contribution: c) Panda, a new steel allele. Haematological studies on the male-fertile black-eared and black-eyed white mutant sl<11H> (MNL 73: 17) have shown that the homozygote suffers from mild macrocytic anaemia, with RBC values from 6.3 to 8.6 x 10<-9>ml<-1> and mean cell volumes from 63 to 50 um<3> in 10 mice. This contrasts with mean values of 10.0 +/- 0.2 x 10<9> for RBC's and 47.6 +/- 0.8 um<3> for mean cell volumes in wild type mice. Treatment with gonadotrophins has failed to overcome the sterility of homozygous females. In future Sll<11H> will be known as panda, Sl<pan>, in view of the homozygote's characteristic pattern of head pigmentation and its clear-cut differences from other Sl mutants. (Beechey, Loutit, Searle) (Supported by EURATOM grant BI6-150-UK)
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