Primary Identifier | MGI:1856236 | Allele Type | Spontaneous |
Gene | Kit | Inheritance Mode | Semidominant |
Strain of Origin | C57BL/6J | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Direct sequence of this allele and comparison with normal c-kit indicated a nonsynonymous coding mutation of a G-to-A point mutation in ATP biding loop consensus sequence of the kinase domain that result in replacement of the glycine with a glutamate residue at amino acid 595 position (p.G595E). |