|  Help  |  About  |  Contact Us

Allele : Kit<W-39J> KIT proto-oncogene receptor tyrosine kinase; dominant spotting 39 Jackson

Primary Identifier  MGI:1856242 Allele Type  Spontaneous
Gene  Kit Inheritance Mode  Semidominant
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  Direct sequence of this allele and comparison with normal c-kit indicated a nonsynonymous coding mutation of a G-to-T point mutation in ATP biding loop consensus sequence of the kinase domain that result in replacement of the methionine with an isoleucine residue at amino acid 623 position (p.M623I).
  • mutations:
  • Single point mutation
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele