|  Help  |  About  |  Contact Us

Allele : Kit<W-40J> KIT proto-oncogene receptor tyrosine kinase; dominant spotting 40 Jackson

Primary Identifier  MGI:1856243 Allele Type  Spontaneous
Gene  Kit Inheritance Mode  Semidominant
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  Direct sequence of this allele and comparison with normal c-kit indicated a nonsynonymous coding mutation of a 5-bp deletion in N-term extracellular domain that result in a frameshift yielding two nonsynonymous substitutions (R186C and A188S) and an in-frame, premature STOP at position 190.
  • mutations:
  • Intragenic deletion
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele