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Allele : Src<tm2Goka> Rous sarcoma oncogene; targeted mutation 2, Goro Kato

Primary Identifier  MGI:7524671 Allele Type  Targeted
Gene  Src Transmission  Germline
Strain of Origin  129S/SvEv-Gpi1<c> Is Recombinase  false
Is Wild Type  false
molecularNote  A TCC to GCG change resulting in a serine to alanine change at amino acid 75 (p.S75A) in exon 2 introduced a non-phosphorylatable mutation. The targeting vector contained 9 kb of mouse Src sequence containing the 2 bp mutation, and a 3.4 kb HSV-tk-neomycin cassette flanked by a 3.2 kb duplication containing a part of the Src sequence.
  • mutations:
  • Nucleotide substitutions
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele