Primary Identifier | MGI:1856274 | Allele Type | Spontaneous |
Gene | Eif3c | Inheritance Mode | Semidominant |
Strain of Origin | C3H/HeJ | Is Recombinase | false |
Is Wild Type | false |
description | Salient features inferred from noncomplementaton test result report. |
molecularNote | This allele was identified by a noncomplementation test result with Xs. A C-to-T point mutation (G-to-A on forward strand) in exon 9 results in a premature stop codon at arginine codon 303 (p.R303*). A a 50% reduction in total Eif3c mRNA levels is seen in homozygous animals. |