| First Author | Woychik RP | Year | 1985 |
| Journal | Nature | Volume | 318 |
| Issue | 6041 | Pages | 36-40 |
| PubMed ID | 2997621 | Mgi Jnum | J:8077 |
| Mgi Id | MGI:56546 | Doi | 10.1038/318036a0 |
| Citation | Woychik RP, et al. (1985) An inherited limb deformity created by insertional mutagenesis in a transgenic mouse. Nature 318(6041):36-40 |
| abstractText | We have created an insertional mutation that leads to a severe defect in the pattern of limb formation in the developing mouse. The novel recessive mutation is phenotypically identical and non-complementary to two previously encountered limb deformity mutations, and is closely linked to a dominant mutation that gives rise to a related limb dysmorphism. The inserted element thus provides a molecular genetic link with the control of pattern formation in the mammalian embryo. |
