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Allele : Higd1c<em2Chaa> HIG1 domain family, member 1C; endonuclease-mediated mutation 2, Andy J Chang

Primary Identifier  MGI:7587821 Allele Type  Endonuclease-mediated
Attribute String  Hypomorph Gene  Higd1c
Inheritance Mode  Not Specified Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
molecularNote  CRISPR-cas9 mediated recombination using gRNAs targeting exon 3 created a 1 bp deletion resulting in a frameshift mutation. Levels of mRNA are reduced by 40-90% in the carotid body and kidneys from homozygous mice.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • 1-1,
  • 1-1
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

3 Publication categories

Trail: Allele