| First Author | Sheng J | Year | 2017 |
| Journal | Cell Rep | Volume | 21 |
| Issue | 5 | Pages | 1203-1214 |
| PubMed ID | 29091760 | Mgi Jnum | J:255235 |
| Mgi Id | MGI:6104060 | Doi | 10.1016/j.celrep.2017.10.024 |
| Citation | Sheng J, et al. (2017) A Discrete Subset of Monocyte-Derived Cells among Typical Conventional Type 2 Dendritic Cells Can Efficiently Cross-Present. Cell Rep 21(5):1203-1214 |
| abstractText | Dendritic cells (DCs) and macrophages (Mvarphis) share close developmental pathways and functional features, leading to blurring of the boundaries between these two cell lineages. However, a deeper understanding of DC and Mvarphi ontogeny and more refined phenotypic and functional characterizations have helped to delineate pre-DC-derived conventional DCs (cDCs), including cDC1s and cDC2s, from monocyte-derived Mvarphis. Here, we further refine DC/Mvarphi cell classification and report that classically defined cDC2s contain a discrete population of monocyte-derived migratory antigen-presenting cells with Mvarphi phenotype but functional DC features, including cross-presentation. |
