First Author | Chamberlain JS | Year | 2010 |
Journal | Cell | Volume | 143 |
Issue | 7 | Pages | 1040-2 |
PubMed ID | 21183068 | Mgi Jnum | J:167707 |
Mgi Id | MGI:4879029 | Doi | 10.1016/j.cell.2010.12.005 |
Citation | Chamberlain JS (2010) Duchenne muscular dystrophy models show their age. Cell 143(7):1040-2 |
abstractText | The lack of appropriate animal models has hampered efforts to develop therapies for Duchenne muscular dystrophy (DMD). A new mouse model lacking both dystrophin and telomerase (Sacco et al., 2010) closely mimics the pathological progression of human DMD and shows that muscle stem cell activity is a key determinant of disease severity. |