| First Author | Müller M | Year | 2007 |
| Journal | Exp Neurol | Volume | 203 |
| Issue | 1 | Pages | 55-62 |
| PubMed ID | 16962581 | Mgi Jnum | J:141511 |
| Mgi Id | MGI:3818409 | Doi | 10.1016/j.expneurol.2006.07.018 |
| Citation | Muller M, et al. (2007) Macrophage colony stimulating factor is a crucial factor for the intrinsic macrophage response in mice heterozygously deficient for the myelin protein P0. Exp Neurol 203(1):55-62 |
| abstractText | Mouse mutants heterozygously deficient for the myelin protein P0 (P0+/-) resemble certain forms of human hereditary neuropathies. Endoneurial macrophages of intrinsic origin are intimately involved in the pathogenesis of the demyelinating neuropathy in these mutants. We have previously shown that deficiency for macrophage colony stimulating factor (M-CSF) prevents an increase of the number of endoneurial macrophages and alleviates the mutants' demyelinating phenotype. The aim of this study was to investigate which population of endoneurial macrophages - long-term resident macrophages or recently infiltrated macrophages |
