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Publication : cDNA approaches to isolation of the mouse mutant weaver gene.

First Author  Hodes ME Year  1994
Journal  Neurochem Res Volume  19
Issue  11 Pages  1359-62
PubMed ID  7898606 Mgi Jnum  J:21869
Mgi Id  MGI:69770 Doi  10.1007/BF00972463
Citation  Hodes ME, et al. (1994) cDNA approaches to isolation of the mouse mutant weaver gene. Neurochem Res 19(11):1359-62
abstractText  The mouse autosomal recessive mutant gene weaver (wv) results in abnormalities in cerebellum, substantia nigra and testis. Although a substracted cDNA library prepared by removing P31 (wv/wv) sequences from a P1 (wv/+) library should contain mainly nonrepetitive neonatal sequences, unfortunately, repetitive sequences still appear during screening. Two clones, one repetitive, the other not, are used to illustrate the problems encountered in attempting to isolate the weaver gene from a substrated cDNA library.
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