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Allele : Fasl<gld> Fas ligand; generalized lymphoproliferative disease

Primary Identifier  MGI:1856384 Allele Type  Spontaneous
Gene  Fasl Inheritance Mode  Recessive
Strain of Origin  C3H/HeJ Is Recombinase  false
Is Wild Type  false
molecularNote  A T-to-C transition point mutation near the 3' end of the coding sequence causes a replacement of a highly conserved phenylalanine with a leucine at position 273 (p.F273L) in the extracellular region of the encoded protein.
  • mutations:
  • Single point mutation
  • synonyms:
  • CD95-,
  • FasL-,
  • gld,
  • gld,
  • Tnfsf6<gld>,
  • Tnfsf6<gld>,
  • FasL-,
  • CD95-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

26 Carried By

Trail: Allele

0 Driven By

368 Publication categories

Trail: Allele