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Allele : Mip<Hfi> major intrinsic protein of lens fiber; hydropic fibers

Primary Identifier  MGI:1856608 Allele Type  Radiation induced
Gene  Mip Inheritance Mode  Semidominant
Strain of Origin  (101 x C3H)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  A 76 bp deletion that removes 17 bp from the 3' end of exon 2 and 59 bp of intron 2. In the encoded mRNA, 165 bp of coding sequence is removed resulting from exon 2 being skipped during the splicing process. By immunoblot analysis on lens cell memebrane preparations, a smaller mutant protein was detected in homozygous mutant mice, although at lower levels that the wild-type protein.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • 538,
  • 538
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele