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Publication : The genetics of blind--a lethal factor in mice.

First Author  Teicher LS Year  1978
Journal  J Hered Volume  69
Issue  2 Pages  86-90
PubMed ID  670679 Mgi Jnum  J:6008
Mgi Id  MGI:54485 Doi  10.1093/oxfordjournals.jhered.a108910
Citation  Teicher LS, et al. (1978) The genetics of blind--a lethal factor in mice. J Hered 69(2):86-90
abstractText  The linkage relationships of the lethal gene blind (Bld) in the mouse were investigated. The gene is located on chromosome 15, between uw and bt. The distance uw--Bld is 28.2 +/- 5.1 cM: Bld--bt is 14.9 +/- 2.7 cM: and Bld--Ca is 24.6 +/- 2.6 cM. Incomplete penetrance and/or reduced viability of Bld/+ animals was found when blind animals were crossed to several strains, but the cross female DBA/2J X male blind yielded complete penetrance and specificity. Evidence is presented for the presence of X-linked modifiers affecting the penetrance and possible increased viability of Bld in strain DBA.
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