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Publication : Cerebellar nitric oxide synthase activity is reduced in nervous and Purkinje cell degeneration mutants but not in climbing fiber-lesioned mice.

First Author  Ikeda M Year  1993
Journal  Neurosci Lett Volume  155
Issue  2 Pages  148-50
PubMed ID  7690917 Mgi Jnum  J:21353
Mgi Id  MGI:66605 Doi  10.1016/0304-3940(93)90694-g
Citation  Ikeda M, et al. (1993) Cerebellar nitric oxide synthase activity is reduced in nervous and Purkinje cell degeneration mutants but not in climbing fiber-lesioned mice. Neurosci Lett 155(2):148-50
abstractText  We measured nitric oxide synthase activity in nervous, Purkinje cell degeneration mutant mice and 3-acetylpyridine-treated mice to determine the cellular localization of nitric oxide synthase in the cerebellum. Nitric oxide synthase activity per cerebellum was reduced to less than 50% of that of controls in nervous and Purkinje cell degeneration mutants, while in 3-acetylpyridine-treated mice there was no reduction.
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