First Author | Cowing C | Year | 1977 |
Journal | J Immunol | Volume | 119 |
Issue | 1 | Pages | 256-62 |
PubMed ID | 68973 | Mgi Jnum | J:5836 |
Mgi Id | MGI:54313 | Doi | 10.4049/jimmunol.119.1.256 |
Citation | Cowing C, et al. (1977) Immunologic tolerance to heterologous immunoglobulin: its relation to in vitro filtration by macrophages. J Immunol 119(1):256-62 |
abstractText | The cellular and molecular basis for the difference in ability of BCG to induce tolerance in BALB/c and DBA/2 mice has been examined by in vitro biofiltration. It was found that incubation with the adherent cells from BALB/c but not DBA/2 spleens could remove the material from BGG which inhibited tolerance induction in BALB/c mice. This material was shown to represent only a trace component in BGG, was present in only certain commercial batches of BGG, and was apparently unrelated to the presence of aggregates or endotoxin. |